Antarctic fungi with antibiotic potential isolated from Fort William Point



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Antarctic fungi with antibiotic potential isolated from Fort William Point

As reported by a study published on the Scientific reports, a group of researchers would have isolated a group of fungi with antibiotic potential, in Antarctica, from Fort Williams Point. The title of the research is Antarctic fungi with antibiotic potential isolated from Fort William Point, Antarctica.

The researchers explained: "The Antarctic continent is one of the most inhospitable places on earth, where living creatures, mostly represented by microorganisms, have specific physiological characteristics that allow them to adapt to the extreme environmental conditions.

These physiological adaptations can result in the production of unique secondary metabolites with potential biotechnological applications. The current study presents a genetic and antibacterial characterization of four Antarctic fungi isolated from soil samples collected in Pedro Vicente Maldonado Scientific Station, at Fort William Point, Greenwich Island, Antarctica.Based on the sequences of the internal transcribed spacer (ITS) region, the fungi were identified as Antarctomyces sp., Thelebolus sp., Penicillium sp., and Cryptococcus gilvescens.

The antibacterial activity was assessed against four clinical bacterial strains: Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Staphylococcus aureus, by a modified bacterial growth inhibition assay on agar plates.

Results showed that C. gilvescens and Penicillium sp. have potential antibiotic activity against all bacterial strains. Interestingly, Thelebolus sp. showed potential antibiotic activity only against E. coli. In contrast, Antarctomyces sp.

did not show antibiotic activity against any of the bacteria tested under our experimental conditions. This study highlights the importance of conservation of Antarctica as a source of metabolites with important biomedical applications.

The bioassays were performed with a minimum of three replicates, and the mean inhibition zone was calculated by measuring the border of the fungi colony to the border of the bacterial growth. This was photographed and measured in millimeters (mm) using the Motic Images Plus 2.0 software.

The software SPSS 19 was used for the statistical analysis of the bacterial inhibition zone around the mycelia plug. The heterogeneity between days of growth was determined by applying Kruskal–Wallis and Mann–Whitney tests, with a statistical confidence level of 95%."