Persistent organic pollutants in foods

A study makes an interesting retrospective on a topic that is very important, especially with an eye to the future, to the generations that surround us they will be after us

by Lorenzo Ciotti
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Persistent organic pollutants in foods

Persistent organic pollutants in foods, their interplay with gut microbiota and resultant toxicity, study published on the The Science of the total environment, makes an interesting retrospective on a topic that is very important, especially with an eye to the future, to the generations that surround us they will be after us.

Generations that will unfortunately have to deal with pollution that will be increasingly endemic. Maybe it's not too late yet, but the situation is certainly borderline. The future is yet to be evaluated, but the presses for now are not good.

The researchers explain: "Persistent Organic Pollutants (POPs) have become immensely prevalent in the environment as a result of their unique chemical properties (persistent, semi-volatile and bioaccumulative nature). Their occurrence in the soil, water and subsequently in food has become a matter of concern.

With food being one of the major sources of exposure, the detrimental impact of these chemicals on the gut microbiome is inevitable.The gut microbiome is considered as an important integrant for human health. It participates in various physiological, biochemical thus, affects the metabolism and physiology of the host.A myriad of studies have corroborated an association between POP-induced gut microbial dysbiosis and prevalence of disorders."

Persistent organic pollutants in foods

Researchers then added: "For instance, ingestion of polychlorinated biphenyls, polybrominated diphenyl ethers or organochlorine pesticides influenced bile acid metabolism via alteration of bile salt hydrolase activity of Lactobacillus, Clostridium or Bacteroides genus.

At the same time, some chemicals such as DDE have the potential to elevate Proteobacteria and Firmicutes/Bacteriodetes ratio influencing their metabolic activity leading to enhanced short-chain fatty acid synthesis, ensuing obesity or a pre-diabetic state.

This review highlights the impact of POPs exposure on the gut microbiota composition and metabolic activity, along with an account of its corresponding consequences on the host physiology. The critical role of gut microbiota in preventing the POPs excretion out of the body resulting in their prolonged exposure and consequently, enhanced degree of toxicity is also emphasized."