Air pollution exposure on acute coronary syndrome



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Air pollution exposure on acute coronary syndrome

Impact of short-term air pollution exposure on acute coronary syndrome in two cohorts of industrial and non-industrial areas: A time series regression with 6,000,000 person-years of follow-up (ACS - Air Pollution Study), published on the Environmental research, is a very retrospective on a topic which show again the close link between human health and pollution of the envirnment, of the air and of the waters.

Basically, the study explained: "Coronary artery disease (CAD) is caused by the formation of atherosclerotic plaques in coronary arteries. This process progresses over time and is aggravated by traditional as well as novel risk factors.

Almost 7 in 10 cases of CAD can be linked to typical risk factors such as high blood pressure, smoking, socioeconomic status, dyslipidemia, poor diet, obesity, diabetes, depression, and air pollution. The data of air pollution and gases were obtained from Voivodeship Inspectorate for Environmental Protection in non-industrial area (Bialystok) and industrial area (Katowice).

The daily meteorological data, including temperature, daily level of relative humidity, mean atmospheric pressure, and rainfall for the same period, were obtained from the Institute of Meteorology and Water Management. Data on hospitalization for ACS were obtained and extracted from the National Health Fund reports.

In the present analysis, we used data from patients registered as residents in the city of Bialystok (id commune 2061011) and Katowice city (id commune 2469011) from January 1, 2008 to December 31, 2017. The risk of air pollution-related ACS was higher in industrial over non-industrial area.

The effects of NO2 on the incidence of NSTEMI were observed in both areas. Additionally, in an industrial area the effects of PMs and SO2 on NSTEMI and STEMI were observed. A negative clinical effect was more delayed in time for NSTEMI patients, especially after exposure to PMs.

Chronic exposure to elevated air pollution levels causes increased progression and destabilization of atherosclerotic plaque and may underlie the differences in the short-term effect between particulate air pollution impact on the incidence of STEMI.

This finding can caution policymakers to design better care services for patients who are at risk of ACS during the periods of increased air pollution in their cities."