Electronic cigarette affects the vascular system

The study How Electronic Cigarette Affects the Vascular System, published in the Journal of smoking cessation, made a review on the issue

by Lorenzo Ciotti
Electronic cigarette affects the vascular system

E-cigarette vapor has a different composition than cigarette smoke and can have lower levels of some toxic chemicals. E-cigarettes reduce lung function, reduce heart muscle function, and increase inflammation. Traditional cigarettes have a longer streak of damage than vaping, however inhaling nicotine has its consequences.

The deadly 2019-2020 vaping lung injury epidemic in North America was caused primarily by the vitamin E acetate in THC-containing vaping liquid. Other unidentified chemicals can also cause lung damage associated with vaping.

The relationship between vaping nicotine intake and tobacco smoking is an area of active study and debate, regarding the related health risks, whether or not e-cigarettes should be promoted as a less harmful alternative of smoking or as a way to quit entirely with nicotine, and whether the availability of e-cigarettes leads more people to become addicted to nicotine.

Nicotine vaping products produce more carcinogens and toxicants than a medically approved nicotine inhaler. Another issue is whether people in the vicinity inhale the vapor exhaled by others, similar to secondhand smoke. The study How Electronic Cigarette Affects the Vascular System, published in the Journal of smoking cessation, explained: "The popularity of the electronic cigarette has soared in the last decades.

However, the health effect of smoking electronic cigarettes on the vascular system is unclear. This systematic review examines the electronic cigarettes' effect on the vascular system from recent evidence. A systematic search was conducted in MEDLINE (PubMed) database from January 2016 to August 2021 for studies assessing the vascular effect of chronic use of electronic cigarettes on human and animal.The Cochrane Risk of Bias 2, NIH Quality Assessment for Cross-Sectional Study, and SYRCLE's Risk of Bias were used to assess the risk of bias in interventional, observational, and animal study, respectively.

A narrative synthesis of evidence is provided to describe results.From 101 retrieved studies related to electronic cigarettes effect on the vascular system, a total of 16 studies are included in this review. The overall results indicated that electronic cigarette use is associated with adverse events in the vascular, including the incident of elevated oxidative stress, endothelial dysfunction, inflammation, arterial stiffness, and the development of atherosclerotic lesion.

Further studies should broaden perspectives and reveal more about the mechanism of how electronic cigarettes impact on vascular system."